IL-22RA2 Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-00119

Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

IL-22RA2 Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-00119

Pack Size	Price	Availability
10 μg	$129	7-10 days
50 μg	$390	7-10 days
500 μg	$1,900	7-10 days
1 mg	$2,730	7-10 days

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User Guide of Recombinant Proteins

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Product Information

Biological Activity	Immobilized Recombinant Human IL-22 (E. Coli) at 2μg/ml (100 μl/well) can bind Recombinant Human IL-22RA2 (C-Fc). The ED50 of Recombinant Human IL-22RA2 (C-Fc) is 34.43 ng/ml. (Regularly tested)
Description	Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q969J5-2
Synonyms	Interleukin-22-Bind,Interleukin-22 Receptor Subunit α-2,Interleukin-22 Receptor Subunit Alpha-2,IL-22R-α-2,IL-22R-Alpha-2,IL-22RA2,IL-22 Receptor Subunit α-2,IL-22 Receptor Subunit Alpha-2,Cytokine Receptor Family Type 2 Soluble 1,Cytokine Receptor Family 2 Member 10,Cytokine Receptor Class-II Member 10,CRF2-S1,CRF2-10
Amino Acid	Thr22-Pro231
Construction	Thr22-Pro231
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	80-100 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.