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IL-22RA2 Protein, Human, Recombinant (hFc)
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IL-22RA2 Protein, Human, Recombinant (hFc)
Catalog No. TMPJ-00119
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 μg | $129 | 7-10 days | |
| 50 μg | $390 | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | |
| 1 mg | $2,730 | 7-10 days |
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Biological Description
| Biological Information | Immobilized Recombinant Human IL-22 (E. Coli) at 2μg/ml (100 μl/well) can bind Recombinant Human IL-22RA2 (C-Fc). The ED50 of Recombinant Human IL-22RA2 (C-Fc) is 34.43 ng/ml. (Regularly tested) |
| Description | Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q969J5-2 |
| Synonyms | Cytokine Receptor Family 2 Member 10,CRF2-10,IL-22RA2,Interleukin-22 Receptor Subunit α-2,Interleukin-22-Bind,IL-22R-α-2,Interleukin-22 Receptor Subunit Alpha-2,IL-22 Receptor Subunit Alpha-2,Cytokine Receptor Family Type 2 Soluble 1,Cytokine Receptor Class-II Member 10,CRF2-S1,IL-22R-Alpha-2,IL-22 Receptor Subunit α-2 |
| Amino Acid | Thr22-Pro231 |
| Construction | Thr22-Pro231 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Molecular Weight | 80-100 KDa (reducing condition) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
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