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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $700 | 7-10 days |
Biological Information | Testing in progress |
Description | INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout results in spermatogenic failure. Human and rat INSL6 encoded polypeptides of 213 and 188 amino acids, respectively. Diseases associated with INSL6 include Thrombocythemia 3 and Lymphoblastic Leukemia, Acute, With Lymphomatous Features. |
Species | Human |
Expression System | HEK293 Cells |
Tag | C-His |
Accession Number | Q9Y581 |
Synonyms | RIF1,insulin-like 6 |
Construction | The Human INSL6 (NP_009110.2) (Met1-Phe198) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity | > 90 % as determined by SDS-PAGE. |
Molecular Weight | 22.1 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout results in spermatogenic failure. Human and rat INSL6 encoded polypeptides of 213 and 188 amino acids, respectively. Diseases associated with INSL6 include Thrombocythemia 3 and Lymphoblastic Leukemia, Acute, With Lymphomatous Features. |
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