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MST3 Protein, Human, Recombinant (His)

Catalog No. TMPY-04424

Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury.

MST3 Protein, Human, Recombinant (His)

MST3 Protein, Human, Recombinant (His)

Catalog No. TMPY-04424
Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury.
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50 μg$498In Stock
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Product Information

Biological Activity
The specific activity was determined to be >30 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.
Description
Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury.
Species
Human
Expression System
Baculovirus Insect Cells
TagN-His
Accession NumberQ9Y6E0-2
Synonyms
STK3,STE20,serine/threonine kinase 24,RP11-111L24.5,MST3B,MST3,HEL-S-95
Construction
A DNA sequence encoding the human STK24 isoform A (Q9Y6E0-2) (Met 1-His 431) was expressed, with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
Protein Purity
> 82 % as determined by SDS-PAGE
Molecular Weight50.3 kDa (predicted); 55 kDa (reducing conditions)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 20% gly, 0.1 mM EGTA, 0.1 mM EDTA, 0.25 mM DTT.
Reconstitution
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage
It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingShipping with blue ice.
Research Background
Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury.

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