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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $1,050 | 7-10 days | |
500 μg | $4,200 | 7-10 days | |
1 mg | $6,990 | 7-10 days |
Description | Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 76.6 kDa and the accession number is A0A2K5USI5. |
Species | Cynomolgus |
Expression System | E. coli |
Tag | N-His |
Accession Number | A0A2K5USI5 |
Synonyms | PDI5,HL-60,PAD,PADI5,Protein-arginine deiminase type-4,HL60 PAD,PAD4,HL-60 PAD |
Construction | Met1-Pro663 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | 76.6 kDa (predicted) same as Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 10% Glycerol, 0.5 mM TCEP, 1 mM EDTA (pH 8.0). |
Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. |
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