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PODXL Protein, Human, Recombinant (hFc)

Catalog No. TMPY-07170

PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592.

PODXL Protein, Human, Recombinant (hFc)

PODXL Protein, Human, Recombinant (hFc)

Catalog No. TMPY-07170
PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592.
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100 μg$687Backorder
1 mg$4,560Backorder
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Product Information

Biological Activity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberO00592
Synonyms
PODXL1,PDX,PCLP-1,PCLP1,PCLP,PC,Gp200,gp135
Construction
A DNA sequence encoding the Human PODXL (O00592) (Ser23-Pro461) was expressed with the Fc region of human IgG1 at the C-terminus.
Protein Purity
≥ 90% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
Molecular Weight72.06 kDa (predicted); 146.2 kDa (reducing contition, due to glycosylation)
Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
FormulationLyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution
Please refer to the lot-specific COA.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer.

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Please read the User Guide of Recombinant Proteins for more specific information.