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PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $687 | Backorder | |
1 mg | $4,560 | Backorder |
Biological Activity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
Description | PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592. |
Species | Human |
Expression System | HEK293 Cells |
Tag | C-hFc |
Accession Number | O00592 |
Synonyms | PODXL1,PDX,PCLP-1,PCLP1,PCLP,PC,Gp200,gp135 |
Construction | A DNA sequence encoding the Human PODXL (O00592) (Ser23-Pro461) was expressed with the Fc region of human IgG1 at the C-terminus. |
Protein Purity | ≥ 90% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC. |
Molecular Weight | 72.06 kDa (predicted); 146.2 kDa (reducing contition, due to glycosylation) |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
Reconstitution | Please refer to the lot-specific COA. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer. |
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