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PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592.
Pack Size | Price | Availability | Quantity |
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Biological Activity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
Description | PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592. |
Protein Purity | ≥ 90% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC. |
Molecular Weight | 72.06 kDa (predicted); 146.2 kDa (reducing contition, due to glycosylation) |
Research Background | Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer. |
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