PSMA Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-00521

Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 80.6 kDa and the accession number is A0A2K5VNZ0.

PSMA Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-00521

Pack Size	Price	Availability
100 μg	$534	7-10 days
500 μg	$2,140	7-10 days
1 mg	$3,570	7-10 days

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Product Information

Biological Activity	Immobilized Cynomolgus PSMA, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-PSMA Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).
Description	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 80.6 kDa and the accession number is A0A2K5VNZ0.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	N-His
Accession Number	A0A2K5VNZ0
Synonyms	PSMAFGCP,PSMA,PSM,NAALADase I,NAALAdase,NAALAD1,mGCP,GIG27,GCPIImGCP,GCPII,GCP2,FOLHNAALADase I,FOLH1,FOLH,Folate hydrolase 1,FGCP
Construction	Lys44-Ala750
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	80.6 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells.