REG2 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPY-03716

REG2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.6 kDa and the accession number is Q08731.

REG2 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPY-03716

REG2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.6 kDa and the accession number is Q08731.

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Product Information

Biological Activity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	REG2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.6 kDa and the accession number is Q08731.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q08731
Synonyms	RegII,regenerating islet-derived 2,REG2
Construction	A DNA sequence encoding the mouse REG2 (NP_033069.1) (Met1-Ala173) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gln 23
Protein Purity	> 95 % as determined by SDS-PAGE
Molecular Weight	43.6 kDa (predicted); 45.4 kDa (reducing conditions)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Regenerating islet-derived proteins (Regs) comprise the superfamily of C-type lectin proteins encoded by Reg1, Reg2, Reg3a, Reg3b, Reg3g, Reg3d, and Reg4. The Reg family proteins are expressed in various tissues and have pleiotropic functions. Reg3b and Reg3g encode murine Reg3β and Reg3γ, respectively, and are murine homolog of human REG3A. Both proteins are highly expressed in the small intestine of adult mice at both mRNA and protein levels, but their expression is very low in the colon. Intriguingly, expression of Reg3β and Reg3γ is not detectable in the embryonic mouse intestine but gradually increases along with colonization of the commensal bacteria after birth.