Shopping Cart
- Remove All
![TargetMol](https://newstatic.targetmol.com/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $801 | 7-10 days | |
1 mg | $5,220 | 7-10 days |
Biological Information | Immobilized Cynomolgus SLC39A6/LIV-1 His at 2 μg/mL (100 μL/well) can bind Rabbit Anti-SLC39A6/LIV-1 Antibody, the EC50 of Rabbit Anti-SLC39A6/LIV-1 Antibody is 15-100 ng/mL. |
Description | Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as an estrogen-induced gene in a breast cancer cell line. Generally, elevated SLC39A6 expression is reportedly related to cancer progression in other various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers. |
Species | Cynomolgus |
Expression System | HEK293 Cells |
Tag | C-His |
Accession Number | A0A2K5WH46-1 |
Synonyms | solute carrier family 39 member 6 |
Construction | The cynomolgus SLC39A6 (A0A2K5WH46-1) (Met1-Gln308) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity | > 95 % as determined by SDS-PAGE. |
Molecular Weight | 34 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM MES, 150 mM NaCl, 10% glycerol, 0.02% Tween 80, pH 6. 0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as an estrogen-induced gene in a breast cancer cell line. Generally, elevated SLC39A6 expression is reportedly related to cancer progression in other various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers. |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.