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SLC39A6 Protein, Human, Recombinant (HEK293, His)

Catalog No. TMPY-07157

SLC39A6 Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is Q13433-1.

SLC39A6 Protein, Human, Recombinant (HEK293, His)

SLC39A6 Protein, Human, Recombinant (HEK293, His)

Catalog No. TMPY-07157
SLC39A6 Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is Q13433-1.
Pack SizePriceAvailabilityQuantity
100 μg $617Backorder
1 mg $3,930Backorder
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Product Information

Biological Activity
Immobilized SLC39A6 Protein, Human, Recombinant (HEK293, His) (Cat#TMPY-07157) at 2 μg/mL (100 μL/well) can bind Anti-LIV-1 Antibody, the EC50 is 5-15 ng/mL.
Description
SLC39A6 Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is Q13433-1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberQ13433-1
Synonyms
ZIP6,LIV-1,LIV1
Construction
A DNA sequence encoding the Human SLC39A6 (Q13433-1) (Phe29-Trp325) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity
≥ 90% as determined by SDS-PAGE.
Molecular Weight35.08 kDa (predicted); 55.2 kDa (reducing contition, due to glycosylation)
Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
FormulationLyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution
Please refer to the lot-specific COA.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as an estrogen-induced gene in a breast cancer cell line. Generally, elevated SLC39A6 expression is reportedly related to cancer progression in other various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers.

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Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.