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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 μg | $129 | 7-10 days | |
50 μg | $390 | 7-10 days | |
500 μg | $1,900 | 7-10 days | |
1 mg | $2,730 | 7-10 days |
Description | Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus. |
Species | Human |
Expression System | E. coli |
Tag | C-6xHis |
Accession Number | P42167 |
Synonyms | Thymopoietin-Related Peptide Isoforms β/γ,Splenin,TMPO,TP,TP5,LAP2,Lamina-Associated Polypeptide 2 Isoforms Beta/Gamma,TPRP Isoforms β/γ,Thymopentin,Thymopoietin-Related Peptide Isoforms Beta/Gamma,Thymopoietin Isoforms Beta/Gamma,TP β/γ,TP Beta/γ,Lamina-Associated Polypeptide 2 Isoforms β/γ,Thymopoietin,TPRP Isoforms Beta/Gamma,Thymopoietin Isoforms β/γ,TP Beta/Gamma |
Amino Acid | Met1-Glu187 |
Construction | Met1-Glu187 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 27 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus. |
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