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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $462 | 7-10 days |
Biological Information | Testing in progress |
Description | TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregulin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 58.5 kDa and the accession number is Q8IYR6-1. |
Species | Human |
Expression System | HEK293 Cells |
Tag | C-hFc |
Accession Number | Q8IYR6-1 |
Synonyms | TR-1,C9orf2,transmembrane protein with EGF-like and two follistatin-like domains 1,CT120.1,H7365 |
Construction | The Human TMEFF1 (NP_003683.2) (Met1-Val330) was expressed with the Fc region of Human IgG1 at the C-terminus. |
Protein Purity | > 85 % as determined by SDS-PAGE. |
Molecular Weight | 58.5 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. |
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