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ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated

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ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated

Catalog No. TMPY-05592

ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25 kDa and the accession number is Q9BZM5.

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Pack Size	Price	Availability
20 μg	$203	In Stock
100 μg	$476	7-10 days
200 μg	$812	7-10 days
500 μg	$1,640	7-10 days

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Biological Description

Biological Information	Testing in progress
Description	ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25 kDa and the accession number is Q9BZM5.
Species	Human
Expression System	HEK293 Cells
Tag	His, Avi
Accession Number	Q9BZM5
Synonyms	ALCAN-α,NKG2DL2,RAET1H,UL16 binding protein 2,N2DL2,ALCAN-alpha,UNQ463 / PRO791
Construction	The Human ULBP2 (NP_079493.1) (Met1-Ser217) was expressed with a c-terminal polyhistidine tagged AVI tag at the C-terminus. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	25 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.