All rights reserved. Any unauthorized use or reproduction without permission is prohibited.

Signaling Pathway Download

Cat.No.

Product Name

Information

Diseases and Conditions

T3299 AT-406
AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhi... Cancer
T3350 Selonsertib
Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signa... Metabolism
T3940 CID5721353
ID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor). Others
T3668 Galangin
Galangin has anti-proliferation effect on HCC cells. Galangin elicits anti-inflammatory ef... Others
T3674 Hydroxysafflor yellow A
Hydroxysafflor yellow A inhibited adipogenesis by increasing HSL promoter activities. Hy... Others
T3101 NQDI-1
Selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50?= 3?μM, K... Others
T3655 PD-1/PD-L1 inhibitor 1
PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein in... Others
T1493 BH3I-1
BH3I-1 is a Bcl-2 family inhibitor. BH3I-1 appeared to induce a dose- and time-dependent a... Others
T3637 Pifithrin-β hydrobromide
Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis... Others
T3653 MX69
MX69 is the?MDM2/XIAP?inhibitor, used for cancer treatment. MX69 blocks the MDM2 protein-X... Others
T3053 CZC-25146?
CZC-25146 is a potent, selective and metabolically stable LRRK2 inhibitor with IC50 of 4.7... Others
T7020 Z-VAD-FMK (Caspase Inhibitor VI)

Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.

Others
T7019 Z-IETD-FMK
Z-IETD-FMK is a specific Caspase-8 inhibitor. Others
T7005 Ulixertinib (BVD-523, VRT752271)
Ulixertinib (BVD-523, VRT752271) is a potent and reversible ERK1/ERK2 inhibitor with IC50 ... Others
T6965 RG-7112
RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor. Phase 1. Others
T6954 PRIMA-1
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tum... Others
T6948 SC1
Pluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAP... Others
T6910 NSC59984
NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradation and p7... Others
T6909 NSC348884
NSC348884, as a nucleophosmin inhibitor, inhibit cell proliferation and induce apoptosis i... Others
T6852 GSK481
GSK481 is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has b... Others
T6826 Emricasan
Emricasan is a potent irreversible pan-caspase inhibitor. Others
T6818 DEL-22379
DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ~0.5 μM. Others
T6778 BDA-366
BDA-366 is a small-molecule Bcl2-BH4 domain antagonist and binds BH4 with high affinity an... Others
T6763 AT406 (SM-406, ARRY-334543)
AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor o... Others
T6749 A-1331852
A-1331852 is a potent and selectiveBCL-XL inhibitor and may be useful in the treatment of ... Others
T6748 A-1155463
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinit... Others
T3375new Verbascoside
Verbascoside has an antimicrobial activity, notably against Staphylococcus aureus. It can ... Others
T3332 Isosteviol
Stevioside, a common natural sweetener, belongs to tetracyclic diterpene glycosides. The p... Metabolism
T3184 Kevetrin hydrochloride
Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor protein p... Cancer
T3166 VX-11e
VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK (Extracellular Sig... Cancer