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Signaling Pathway Download


Product Name


Diseases and Conditions

T6980 Scriptaid
Scriptaid is an inhibitor of HDAC. It shows a greater effect on acetylated H4 than H3. Others
T3662 Eleutheroside E
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutherosid... Others
T3415 Secoisolariciresinol diglucoside
Secoisolariciresinol Diglucoside was cytoprotective in an in vitro model of iron overload ... Cardiovascular system
T3680 ISO-1
Macrophage migration inhibitory factor (MIF) is a regulator of inflammation that also has ... Others
T2915 CDDO
CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible ... Cancer
T3689 Ruboxistaurin hydrochloride
Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibi... Metabolis
T3661 ACY-241
ACY-241, also known as Citarinostat, is a potent, selective and orally available histone d... Cancer
T3668 Galangin
Galangin has anti-proliferation effect on HCC cells. Galangin elicits anti-inflammatory ef... Others
T3674 Hydroxysafflor yellow A
Hydroxysafflor yellow A inhibited adipogenesis by increasing HSL promoter activities. Hy... Others
T3133 YM-90709
YM-90709 is a novel antagonist which inhibits the binding of interleukin-5 to interleukin-... Others
T3636 SIS3
Selective Smad3 inhibitor; attenuates TGF-β1-dependent Smad3 phosphorylation and DNA bindi... Others
T3094 PS-1145
PS-1145 is a specific?IKK?inhibitor with?IC50?of 88 nM. Cancer/ respiratory system/ Cardiovascular/ Metabolism
T3097 Mycophenolic Acid Impurity
Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be... Others
T6919 Omaveloxolone (RTA-408)
Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective tran... Others
T6867 KD025 (SLx-2119)
KD025 is an orally available, and selective ROCK2 inhibitor with IC50 and Ki of 60 nM and ... Others
T6865 Quisinostat (JNJ-26481585) 2HCl
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest p... Others
T6852 GSK481
GSK481 is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has b... Others
T6771 AZD3264
AZD3264 is a novel IKK2 inhibitor. Others
T0097new MRT67307
MRT67307 is a kinase inhibitor that has been shown to inhibit TBK1, MARK1-4, IKKε, and NUA... Others
T3374new Dihydrotanshinone I
Dihydrotanshinone I (DHTS) was previously reported to exhibit the most potent anti-cancer ... Others
T3375new Verbascoside
Verbascoside has an antimicrobial activity, notably against Staphylococcus aureus. It can ... Others
T3384new Wedelolactone
Wedelolactone inhibits adipogenic differentiation through ERK pathway, may be a novel inhi... Others
T3608new Carbasalate?Calcium
Carbasalate calcium?is an?analgesic,?antipyretic, and?anti-inflammatory?drug,?as well as a... Platelet aggregation
T3612new Carbocisteine
Carbocisteine?is a mucolytic that reduces the viscosity of sputum and so can be used to he... Immunology
T3406new Cyanidin-3-O-glucoside chloride
Cyanidin-3-O-glucoside was recognized as potent antioxidants and free radical scavengers, ... Others
T3614new Isoprinosine
Isoprinosine has a number of immunomodulatory effects, including inducing T-lymphocyte di... Immunology
T3416new Aucubin
Aucubin is an iridoid glycoside with a wide range of biological activities, including anti... Others
T3603new Sodium houttuyfonate
Sodium houttuyfonate is anti-pseudomonas agents, inhibits virulence related motility of Ps... Others
T3419new Chelerythrine chloride
Cell-permeable inhibitor of protein kinase C (IC50?= 660 nM); competitive with respect to ... Cancer
T6270 Trichostatin A (TSA)
Trichostatin A (TSA) is an HDAC inhibitor with IC50 of ~1.8 nM – HDAC8 is the only known m... Cancer
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