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Signaling Pathway Download


Product Name


Diseases and Conditions

T3690 A 740003
Potent and selective P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and hu... Immunology
T3303 ML-277
Potassium (K+) channels are categorized by their mode of activation and the number of tran... Others
T3639 A-804598
A-804598 is a novel, competitive, and selective P2X7 receptor antagonist with IC50 of 10 n... Others
T3135 KM11060
KM11060 is a novel corrector of the F508del-CFTR trafficking defect. Others
T3644 U93631
GABAA?receptor antagonist that binds the picrotoxin site and stabilizes the inactive form ... Others
T3650 STO-609 acetate
Selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki... Others
T3651 YM-58483 (BTP2)
YM-58483 is the first selective and potent inhibitor of?CRAC channels?and subsequent Ca2+?... Others
T7000 Tiagabine hydrochloride
Tiagabine Hydrochloride is the hydrochloride salt form of tiagabine, a nipecotic acid deri... Others
T6977 SB366791
SB-366791 is a novel, potent, and selective, cinnamide TRPV1 antagonist. Others
T6955 Propafenone HCl
Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated... Others
T6929 Pantoprazole sodium
Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It work... Others
T6928 Pantoprazole
Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulcer... Others
T6874 Lercanidipine hydrochloride
Lercanidipine is a calcium channel blocker of the dihydropyridine class. Others
T6848 GSK1016790A
GSK1016790A (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential v... Others
T6834 FCCP
FCCP is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP ... Others
T6796 CB-5083
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor with IC50... Others
T6782 Benzocaine hydrochloride
Benzocaine hydrochloride is a surface anesthetic that acts by preventing transmission of i... Others
T6777 Bay K 8644
Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM. Others
T6106 Selinexor (KPT-330)
Selinexor (KPT-330) is an orally bioavailable selective CRM1 inhibitor. Phase 2. Cardiovascular System
T3547new LX-4211
LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents. Metabolism
T3379new Decanoic Acid
Decanoic acid acts as a non-competitive AMPA receptor antagonist at therapeutically releva... Others
T3432new Cinobufagin
Cinobufagin is a specific Na+/K+-ATPase inhibitor. About as active as ouabain. Cancer/ Immunology
T0132new Etoposide
Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis v... Cancer
T2131 Articaine hydrochloride
Articaine is a dental local anesthetic which contains an additional ester group that is me... Nervous system
T3332 Isosteviol
Stevioside, a common natural sweetener, belongs to tetracyclic diterpene glycosides. The p... Metabolism
T3093 Spermine Tetrahydrochloride
Used for precipitation of DNA of >100 base pairs in length from low salt aqueous buffers. Other
T3210 AZD-3965
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding af... Cancer
T3183 WAY-181187(SAX-187)

WAY-181187 possess high affinity binding (2.2 nM) at the human 5-HT6 receptor and profi...

T6740 Bafilomycin A1
A macrolide antibiotic and potent and selective inhibitor of vacuolar-type H+ ATPase (V-AT... Cancer
T3192 NS1643
NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 ... Other
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