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Product Name


Diseases and Conditions

T3684 CP21R7
CP21R7 is a potent and selective inhibitor of GSK3β.It is used as an activator of stem cel... Others
T3692 GNE 477
GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, ... Others
T3346 AKT inhibitor VIII
Akti-1/2 is a highly selective Akt1/Akt2 inhibitor with IC50 of 58 nM/210 nM, respectively... Others
T3348 PIK-293
PIK-293 is a PI3K inhibitor, mostly for PI3Kδ with IC50 of 0.24 μM, 500-, 100- and 50-fold... Others
T3351 CC-223
CC-223 is an orally available inhibitor of the mammalian target of rapamycin (mTOR) with p... Cancer
T3625 ETC-1002
ETC-1002, also known as ESP-55016 and Bempedoic acid, is an orally available, once-daily L... Metabolism
T3656 PKI-402
PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with IC50 ... Others
T3676 Sesamol

Sesamol could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung inju...

T3132 SC66
SC66 is a novel AKT inhibitor, IC50 values of approximately 0.75 μg/ml at 72 hours in HepG... Others
T3134 Mirin
Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated ... Others
T3153 MLN1117
MLN1117 (INK1117) is a p110 inhibitor which inhibits p110α, p110β, p110γ, p110δ with IC50 ... Cancer
T7015 VPS34-IN1
Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro,whic... Others
T7014 Voxtalisib (XL765, SAR245409)
Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50... Others
T7001 TIC10
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug prop... Others
PIK-III, which is a selective inhibitor of ?VPS34 enzymatic activity, inhibits autophagy a... Others
T6938 PF-4989216
PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM... Others
T6883 LY3023414
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-... Others
T6878 LJI308
LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 n... Others
T6877 LJH685
LJH685 is a potent pan-RSK inhibitor with IC50 of 6 nM, 5 nM and 4 nM for RSK1, RSK2, and ... Others
T6854 GSK621
GSK621 is a specific and potent AMPK activator. Others
T6850 GSK2292767
GSK2292767 is a potent and selective PI3Kδ inhibitor. Others
T6849 Uprosertib (GSK2141795)
Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhib... Others
T6845 GNE-317
GNE-317 is a potent, brain-penetrant PI3K inhibitor. Others
T6817 Deguelin
Deguelin, a natural product isolated from plants in the Mundulea sericea family, is an PI... Others
T6787 BIO-acetoxime
BIO-acetoxime is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity... Others
T6774 AZD8835
AZD8835 ia a novel mixed inhibitor of PI3Kα and PI3Kδ with IC50 of 6.2 nM and 5.7 nM, resp... Others
T6773 AZD8186
AZD8186 is a potent and selective inhibitor of PI3Kβ and PI3Kδ with IC50 of 4 nM and 12 nM... Others
T6770 AZD0156
AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-se... Others
T6757 AMG319
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity ... Others
T3604new DCA
Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism... Metabolism
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