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Signaling Pathway Download

Cat.No.

Product Name

Information

Diseases and Conditions

T3350 Selonsertib
Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signa... Metabolism
T3101 NQDI-1
Selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50?= 3?μM, K... Others
T3632 Doravirine
Doravirine, also known as MK-1439, is a non-nucleoside reverse transcriptase inhibitor und... Immunology
T3064 VTP-27999
VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-... Cardiovascular system/ Metabolism
T7020 Z-VAD-FMK (Caspase Inhibitor VI)

Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.

Others
T7019 Z-IETD-FMK
Z-IETD-FMK is a specific Caspase-8 inhibitor. Others
T7016 VR23
VR23 is a potent proteasome inhibitor with IC50 of 1 nM, 50-100 nM, and 3 μM for trypsin-l... Others
T6999 Teneligliptin hydrobromide
Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; compe... Others
T6986 Sivelestat (ONO-5046)
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM. I... Others
T6941 PI-1840
PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor with IC50 of 27 n... Others
T6935 PF-03084014 (PF-3084014)
PF-03084014 (PF-3084014) is a selective gamma-secretase inhibitor with IC50 of 6.2 nM in a... Others
T6925 P5091 (P005091)
P5091(P005091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7)... Others
T6885 Marimastat(BB-2516)
Marimastat (BB-2516) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-9,... Others
T6870 L-685,458
L-685,458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki... Others
T6861 IMR-1
IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with I... Others
T6830 Epoxomicin
Epoxomicin is a selective proteasome inhibitor with anti-inflammatory activity, inhibits p... Others
T6826 Emricasan
Emricasan is a potent irreversible pan-caspase inhibitor. Others
T6797 CB-839
CB-839 is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of ... Others
T6791 BPTES
BPTES is a potent and selective Glutaminase GLS1 (KGA) inhibitor with IC50 of 0.16 μM. Others
T2324 Darunavir Ethanolate
Darunavir is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFEC... Other
T3388new Calycosin-7-O-beta-D-glucoside
Calycosin 7-O-β-D-glucoside has antimicrobial activity. Calycosin 7-O-β-D-glucoside is ant... Others
T3335 DarunavirEthanolate
Darunavir Ethanolate (DRV) is a nonpeptidic?HIV protease?inhibitor, used to treat HIV infe... Immunology
T3334 Velpatasvir
Velpatasvir, also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhib... Immunology
T2239L Raltegravir
Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC... Immunology
T2239 Raltegravir potassium salt
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, us... Immunology
T0984 5-Fluorouracil
5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting... Cancer
T3172 Trovirdine (LY-300046)
Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/te... Immunology
T3182 L-778123 hydrochloride
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM... Cancer
T3164 ML241
ML241 is a potent and selective inhibitors of p97 ATPase with IC50 values of 100 nM. Cancer
T2470 Calpain Inhibitor III
Calpain Inhibitor III is a Cysteine protease. Others