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Cat.No.

Product Name

Information

Diseases and Conditions

T3160 HUHS015
HUHS015 is a potent PCA-1/ALKBH3 inhibitor. The bioavailability of HUHS015 was 7.2% in rat... Others
T3678 Entrectinib
Entrectinib is an inhibitor of TrkA (IC50= 1.7 nM), TrkB (IC50= 0.1 nM), and TrkC (IC50= 0... Cancer
T3274 S49076
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocke... Cancer
T3312 AM-2394
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphory... Others
T3634 AZD-9291 mesylate
AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and p... Cancer
T3691 SAR131675
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinas... Others
T3599 BFH772
BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 ... Immunology
T3641 BAW2881
BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor rece... Others
T3659 AZD3759
AZD3759 is a potent, oral active, central nervous system-penetrant, EGFR inhibitor. At Km ... Cancer
T3024 Avitinib

Avitinib, also known as AC0010 or AC0010MA, is an orally available, irreversible, epide...

Cancer
T7007 UNC-2025
UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM ... Others
T6996 SU5402
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 3... Others
T6982 SGI-7079
SGI-7079 ,a novel selective Axl inhibitor, inhibits tumor growth in a dose dependent manne... Others
T6943 Picropodophyllin (PPP)
Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM. Phase 1/2. Others
T6934 Pexmetinib (ARRY-614)
Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with... Others
T6932 PD168393
PD168393 is an irreversible EGFR inhibitor with IC50 of 0.70 nM, irreversibly alkylate Cys... Others
T6930 Pazopanib HCl (GW786034 HCl)
Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, ... Others
T6918 Olmutinib (HM61713, BI 1482694)
Olmutinib is a novel third-generation epidermal growth factor receptor (EGFR) mutation-spe... Others
T6908 NSC228155
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulat... Others
T6907 NPS-1034
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively. Others
T6880 LOXO-101
LOXO-101 is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor... Others
T6836 FIIN-2
FIIN-2 is an irreversible, pan-FGFR inhibitor with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3... Others
T6824 EAI045
EAI045 is an allosteric inhibitor that targets selected drug-resistant EGFR mutants but sp... Others
T6756 AMG 925
AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and... Others
T3402new Ginsenoside Rg3
Ginsenoside Rg3 possess an ability to inhibit the lung metastasis of tumor cells via inhib... Others
T3403new Glabridin
Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction... Others
T3550new Ensartinib
Ensartinib, also known as X-396, is an orally available small molecule inhibitor of the re... Cancer
T3441new Anlotinib
Anlotinib is a EGFR inhibitor extracted from patent 2015185012 A1, compound 1,which can be... Cancer
T3337 Ddr1-In-1
DDR1-IN-1 is a potent and selective?discoidin domain receptor 1 (DDR1)?receptor tyrosine k... Others
T2693 AG1024
AG-1024 (Tyrphostin) inhibits IGF-1R autophosphorylation with IC50 of 7 μM, less potent to... Other
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