||KM11060 is a novel corrector of the F508del-CFTR trafficking defect.
||VX-809 (Lumacaftor) acts to correct CFTR mutations common in cystic fibrosis by incre...
||Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR wit...
||GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of ...
||CFTRinh-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, sho...
||VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach ...
||PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride curre...
||PTC124 (Ataluren) selectively induces ribosomal read-through of premature but not nor...
||Ibuprofen (Motrin) is an anti-inflammatory inhibitor targeting COX-1 and COX-2, of wh...
||Lubiprostone is an activator of ClC-2 chloride channels, used in the management of id...