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CFTR
Cat.No. Product Name Information Area
T3135 KM11060 KM11060 is a novel corrector of the F508del-CFTR trafficking defect. Others
T2595 VX-809 VX-809 (Lumacaftor) acts to correct CFTR mutations common in cystic fibrosis by incre... Cancer
T2588 Ivacaftor (VX-770) Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR wit... Cancer
T2451 GlyH-101 GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of ... Other
T2355 CFTR(inh)-172 CFTRinh-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, sho... Other
T2263 VX661 VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach ... Cancer
T1874 PPQ-102 PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride curre... Other
T1805 PTC124 PTC124 (Ataluren) selectively induces ribosomal read-through of premature but not nor... Other
T1394 Ibuprofen Ibuprofen (Motrin) is an anti-inflammatory inhibitor targeting COX-1 and COX-2, of wh... Nervous system
T6307 Lubiprostone Lubiprostone is an activator of ClC-2 chloride channels, used in the management of id... Cardiovascular System
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