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Mdm2
Cat.No. Product Name Information Area
T3517 RO8994 RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2... Others
T3653 MX69 MX69 is the?MDM2/XIAP?inhibitor, used for cancer treatment. MX69 blocks the MDM2 prot... Others
T6965 RG-7112 RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor. Phase ... Others
T6954 PRIMA-1 PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of huma... Others
T3184 Kevetrin hydrochloride Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor prot... Cancer
T6585 MI-773 (SAR405838) MI-773 (SAR405838) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1... Cancer
T6614 Nutlin-3b Nutlin-3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold ... Cancer
T6610 NSC 207895 NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization... Cancer
T6254 Idasanutlin (RG-7388) Idasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM. Cancer
T6149 YH239-EE YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis ... Cancer
T6023 Nutlin-3a Nutlin-3a, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with ... Cancer
T2464 NSC319726 NSC319726 is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing ... Cancer
T2243 Serdemetan Serdemetan(JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces ... Cancer
T2158 Nutlin-3 Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 ... Other
T1919 Tenovin-1 Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitinati... Cancer
T1798 RITA RITA(NSC 652287) induced both DNA-protein and DNA-DNA cross-links with no detectable ... Other
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