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PDE
Cat.No. Product Name Information Area
T3987 E 6005 E6005 is a phosphodiesterase 4 (PDE-4) inhibitor potentially for the treatment of at... Immunology
T3465 Vesnarinone Vesnarinone is a quinolinone derivative, and its pharmacodynamic effects include inhi... Immunology
T6983 Sildenafil Mesylate Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiestera... Others
T6548 Irsogladine Irsogladine is an anti-gastric ulcer agent that facilitates gap-junctional intercellu... Nervous system
T6462 Deltarasin Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM f... Metabolism system
T6649 S-(+)-Rolipram S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM,... Metabolism system
T6390 Anagrelide hydrochloride Anagrelide Hydrochloride(BL4162A) is a drug used for the treatment of essential throm... Metabolism system
T6445 Cilomilast Cilomilast is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammator... Metabolism system
T6644 Rolipram Rolipram is a PDE4 inhibitor and an anti-inflammatory agent. Metabolism system
T6054 GSK256066 GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of... Metabolism system
T6042 PF-2545920 PF-2545920 is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM, with >100... Metabolism system
T2923 Apremilast (CC-10004) Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-α inhibitor with IC5... Metabolism system
T2855 Icariin Icariin(Ieariline) is a major constituent of flavonoids from the Chinese medicinal he... Metabolism system
T2334 Avanafil Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, >121-fold selectiv... Endocrine system
T2137 Ibudilast Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibi... Respiratory system
T2129 Zaprinast Zaprinast was an unsuccessful clinical drug candidate that was a precursor to the che... Respiratory system
T1745 TAK-063 TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of... Other
T1713 IBMX 3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor... Metabolism system
T1708 Pimobendan Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM. Metabolism system
T1681 Aminophylline Aminophylline is a competitive nonselective phosphodiesterase inhibitor that is used ... Respiratory system
T1618 Dipyridamole Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and met... Cardiovascular System
T1398 Tadalafil Tadalafil is an orally adminstered drug used to treat male erectile dysfunction (impo... Endocrine system
T1265 Amrinone A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, ph... Cardiovascular System
T1164 Sildenafil Sildenfail is a vasoactive agent used to treat erectile dysfunction and reduce sympto... Endocrine system
T1112 2-(Hydroxymethyl)pyridine 2-Pyridinylmethanol is an organic compound. Other
T1096 Milrinone Milrinone(Win 47203) is a PDE3 inhibitor that increases intracellular cyclic adenosi... Cardiovascular System
T1083L Theophylline monohydrate A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial... Respiratory system
T1083 Theophylline Theophylline is a methylated xanthine derivative; competitive nonselective phosphodie... Respiratory system
T1024 Roflumilast Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibiti... Respiratory system
T0994 Ketotifen fumarate Ketotifen (fumarate) is a second-generation noncompetitive H1-antihistamine and mast ... Respiratory system
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