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Description | (S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) is a synthesized conjugate combining the VH032-based VHL ligand with a linker designed for use in PROTAC technology, serving as an E3 ligase ligand-linker. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Alias | VH032-PEG1-NH2, (S,R,S)-AHPC-PEG1-NH2 |
Molecular Weight | 531.67 |
Formula | C26H37N5O5S |
Cas No. | 2241641-57-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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