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α-hydroxy Farnesyl phosphonic acid, a nonhydrolyzable analog of farnesyl pyrophosphate, acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations above 1 μM, it inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $296 | 35 days | |
5 mg | $1,350 | 35 days | |
10 mg | $2,400 | 35 days |
Description | α-hydroxy Farnesyl phosphonic acid, a nonhydrolyzable analog of farnesyl pyrophosphate, acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations above 1 μM, it inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells. |
Molecular Weight | 302.35 |
Formula | C15H27O4P |
Cas No. | 148796-53-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | PBS (pH 7.2): <25 μg/mL Ethanol: >25 mg/mL 10 mM Na2CO3: Freely Soluble |
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