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111-Trifluoroethyl-PEG4-amine is a polyethylene glycol (PEG)-based linker appropriate for synthesizing proteolysis-targeting chimeras (PROTACs) [1].
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500 mg | Inquiry | Backorder |
Description | 111-Trifluoroethyl-PEG4-amine is a polyethylene glycol (PEG)-based linker appropriate for synthesizing proteolysis-targeting chimeras (PROTACs) [1]. |
In vitro | PROTACs utilize two distinct ligands connected by a linker: one binds to an E3 ubiquitin ligase, while the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 275.27 |
Formula | C10H20F3NO4 |
Cas No. | 1872433-72-1 |
Relative Density. | 1.151 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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