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1,2,3,4,7,8-Hexachlorodibenzofuran (1,2,3,4,7,8-HxCDF) enhances the expression of CYP1A1, CYP1B1, and aryl hydrocarbon receptor repressor (AhRR) genes in human peripheral blood lymphocytes (PBL). It can activate ethoxyresorufin-O-deethylase (EROD), with a BMR20TCDD within the range of 0.115-0.143 nM, corresponding to 20% of the maximum response induced by TCDD.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | 1,2,3,4,7,8-Hexachlorodibenzofuran (1,2,3,4,7,8-HxCDF) enhances the expression of CYP1A1, CYP1B1, and aryl hydrocarbon receptor repressor (AhRR) genes in human peripheral blood lymphocytes (PBL). It can activate ethoxyresorufin-O-deethylase (EROD), with a BMR20TCDD within the range of 0.115-0.143 nM, corresponding to 20% of the maximum response induced by TCDD. |
Alias | 1,2,3,4,7,8-HxCDF |
Molecular Weight | 374.86 |
Formula | C12H2Cl6O |
Cas No. | 70648-26-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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