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10-keto Naltrexone

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Catalog No. T202683Cas No. 96445-14-6
Alias 10-oxo Naltrexone, 10keto Naltrexone, 10 keto Naltrexone

10-keto Naltrexone is an antagonist of the μ-, κ-, and δ-opioid receptors, exhibiting inhibition constants (Kis) of 31.1, 102, and 281 nM, respectively, at guinea pig receptors.

10-keto Naltrexone

10-keto Naltrexone

😃Good
Catalog No. T202683Alias 10-oxo Naltrexone, 10keto Naltrexone, 10 keto NaltrexoneCas No. 96445-14-6
10-keto Naltrexone is an antagonist of the μ-, κ-, and δ-opioid receptors, exhibiting inhibition constants (Kis) of 31.1, 102, and 281 nM, respectively, at guinea pig receptors.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
10-keto Naltrexone is an antagonist of the μ-, κ-, and δ-opioid receptors, exhibiting inhibition constants (Kis) of 31.1, 102, and 281 nM, respectively, at guinea pig receptors.
Alias10-oxo Naltrexone, 10keto Naltrexone, 10 keto Naltrexone
Chemical Properties
Molecular Weight355.38
FormulaC20H21NO5
Cas No.96445-14-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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