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11-trans Leukotriene D4

Catalog No. T37493Cas No. 79768-40-4
Alias 11-trans Leukotriene D4

11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25% of the potency for contraction of guinea pig ileum, trachea, and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.

11-trans Leukotriene D4
Other Forms of 11-trans Leukotriene D4:
Leukotriene D4T3812873836-78-9
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11-trans Leukotriene D4

Catalog No. T37493Alias 11-trans Leukotriene D4Cas No. 79768-40-4
11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25% of the potency for contraction of guinea pig ileum, trachea, and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.
Pack SizePriceAvailabilityQuantity
50 μg$78335 days
100 μg$1,48035 days
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Product Introduction

Bioactivity
Description
11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25% of the potency for contraction of guinea pig ileum, trachea, and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.
Alias11-trans Leukotriene D4
Chemical Properties
Molecular Weight496.66
FormulaC25H40N2O6S
Cas No.79768-40-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: >50 mg/mL (per Ramki Iyer)
DMSO: >50 mg/mL (per Ramki Iyer)
PBS (pH 7.2): >100 μg/mL (per Ramki Iyer)
Ethanol: >50 mg/mL (per Ramki Iyer)

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

11trans Leukotriene D411-trans Leukotriene D-411 trans Leukotriene D4
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