14,15-Epoxyeicosatrienoic acid

14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances astrocytic Aβ clearance, making it relevant for Alzheimer's Disease research [1][2].

Catalog No. T83451Cas No. 81276-03-1

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14,15-Epoxyeicosatrienoic acid

Catalog No. T83451Cas No. 81276-03-1

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Pack Size	Price	Availability	Quantity
5 mg	Inquiry	8-10 weeks
50 mg	Inquiry	8-10 weeks

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Product Introduction

Bioactivity

Description	14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances astrocytic Aβ clearance, making it relevant for Alzheimer's Disease research [1][2].
In vitro	14,15-Epoxyeicosatrienoic acid (0-10 μM) enhances Aβ uptake in primary astrocyte cultures [1].
In vivo	14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) inhibits platelet aggregation in murine cerebral arterioles [2]. Administration of 14,15-Epoxyeicosatrienoic acid (200 ng/ml) into the hippocampus reverses Aβ deposition in the brains of 6-month-old male FAD mice [1].
Alias	14,15-EET

Chemical Properties

Molecular Weight	320.47
Formula	C₂₀H₃₂O₃
Cas No.	81276-03-1

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