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EM-651

Name: EM-651
Brand: TargetMol
SKU: T60115
Price: -1 EUR
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60115Cas No. 182167-58-4

Alias 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-

EM-651 (2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-) is an enantiomer of EM-652, IC50=20.0 nM. EM-652 is an orally active pure antiestrogen and selective estrogen receptor antagonist, IC50=0.44nM.

EM-651

🥰Excellent

Purity: 99.27%

Catalog No. T60115Alias 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-Cas No. 182167-58-4

Pack Size	Price	Availability
1 mg	185 €	In Stock
2 mg	278 €	In Stock
5 mg	424 €	In Stock
10 mg	Inquiry	In Stock
50 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	496 €	In Stock

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Purity:99.27%

Resource Download

COA HPLC HNMR

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Product Introduction

Bioactivity

Description	EM-651 (2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-) is an enantiomer of EM-652, IC50=20.0 nM. EM-652 is an orally active pure antiestrogen and selective estrogen receptor antagonist, IC50=0.44nM.
Alias	2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-

Chemical Properties

Molecular Weight	457.56
Formula	C₂₉H₃₁NO₄
Cas No.	182167-58-4
Smiles	CC1=C([C@H](OC=2C1=CC=C(O)C2)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5
Relative Density.	1.217 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 45 mg/mL (98.35 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1855 mL	10.9275 mL	21.8551 mL	109.2753 mL
5 mM	0.4371 mL	2.1855 mL	4.3710 mL	21.8551 mL
10 mM	0.2186 mL	1.0928 mL	2.1855 mL	10.9275 mL
20 mM	0.1093 mL	0.5464 mL	1.0928 mL	5.4638 mL
50 mM	0.0437 mL	0.2186 mL	0.4371 mL	2.1855 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

EM 651EM-651EM651