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2-Hydroxysaclofen

2-Hydroxysaclofen is a GABAB receptor antagonist.

Catalog No. T22495Cas No. 117354-64-0

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2-Hydroxysaclofen

Catalog No. T22495Cas No. 117354-64-0

2-Hydroxysaclofen is a GABAB receptor antagonist.

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Pack Size	Price	Availability	Quantity
10 mg	$665	35 days
50 mg	$2,710	35 days

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Product Introduction

Bioactivity

Description

2-Hydroxysaclofen is a GABAB receptor antagonist.

Chemical Properties

Molecular Weight	265.71
Formula	C₉H₁₂ClNO₄S
Cas No.	117354-64-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 5 mMmg

1eq. NaOH: 100 mM

Solution Preparation Table

H2O/1eq. NaOH

	1mg	5mg	10mg	50mg
1 mM	3.7635 mL	18.8175 mL	37.6350 mL	188.1751 mL
5 mM	0.7527 mL	3.7635 mL	7.5270 mL	37.6350 mL

1eq. NaOH

	1mg	5mg	10mg	50mg
10 mM	0.3764 mL	1.8818 mL	3.7635 mL	18.8175 mL
20 mM	0.1882 mL	0.9409 mL	1.8818 mL	9.4088 mL
50 mM	0.0753 mL	0.3764 mL	0.7527 mL	3.7635 mL
100 mM	0.0376 mL	0.1882 mL	0.3764 mL	1.8818 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

2-Hydroxysaclofen2 Hydroxysaclofen2Hydroxysaclofen