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3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid

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Catalog No. T201012

3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) serves as an effective antimicrobial agent, displaying activity against both Gram-positive bacteria and fungi. In addition to its primary use, it can also function as an adjuvant in antibiotic treatments. The mechanism of action for compound J1 involves disrupting bacterial cell membranes, integrating into DNA, and binding with DNA gyrase. Furthermore, it has been shown to reduce microbial counts and accelerate wound healing in a mouse MRSA skin infection model.

3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid

3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid

😃Good
Catalog No. T201012
3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) serves as an effective antimicrobial agent, displaying activity against both Gram-positive bacteria and fungi. In addition to its primary use, it can also function as an adjuvant in antibiotic treatments. The mechanism of action for compound J1 involves disrupting bacterial cell membranes, integrating into DNA, and binding with DNA gyrase. Furthermore, it has been shown to reduce microbial counts and accelerate wound healing in a mouse MRSA skin infection model.
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Product Introduction

Bioactivity
Description
3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) serves as an effective antimicrobial agent, displaying activity against both Gram-positive bacteria and fungi. In addition to its primary use, it can also function as an adjuvant in antibiotic treatments. The mechanism of action for compound J1 involves disrupting bacterial cell membranes, integrating into DNA, and binding with DNA gyrase. Furthermore, it has been shown to reduce microbial counts and accelerate wound healing in a mouse MRSA skin infection model.
Chemical Properties
Molecular Weight596.89
FormulaC36H60N4O3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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