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4-Oxoisotretinoin

Name: 4-Oxoisotretinoin
Brand: TargetMol
SKU: T3559
Price: 58 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T3559Cas No. 71748-58-8

Alias Ro 22-6595, Oxoretinoic acid, 4-Oxoisotretinoin

4-Oxoisotretinoin (Ro 22-6595) is the major blood metabolite.

4-Oxoisotretinoin

Purity: 95.8%

Catalog No. T3559Alias Ro 22-6595, Oxoretinoic acid, 4-OxoisotretinoinCas No. 71748-58-8

4-Oxoisotretinoin (Ro 22-6595) is the major blood metabolite.

Pack Size	Price	Availability
1 mg	$58	In Stock
2 mg	$105	In Stock
5 mg	$126	In Stock
10 mg	$177	In Stock
25 mg	$319	In Stock
50 mg	$423	In Stock
100 mg	$619	In Stock
500 mg	$1,330	In Stock
1 mL x 10 mM (in DMSO)	$136	In Stock

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Purity:95.8%

Resource Download

COA HNMR HPLC

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Product Introduction

Bioactivity

Description	4-Oxoisotretinoin (Ro 22-6595) is the major blood metabolite.
Alias	Ro 22-6595, Oxoretinoic acid, 4-Oxoisotretinoin

Chemical Properties

Molecular Weight	314.42
Formula	C₂₀H₂₆O₃
Cas No.	71748-58-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (174.93 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1805 mL	15.9023 mL	31.8046 mL	159.0230 mL
5 mM	0.6361 mL	3.1805 mL	6.3609 mL	31.8046 mL
10 mM	0.3180 mL	1.5902 mL	3.1805 mL	15.9023 mL
20 mM	0.1590 mL	0.7951 mL	1.5902 mL	7.9511 mL
50 mM	0.0636 mL	0.3180 mL	0.6361 mL	3.1805 mL
100 mM	0.0318 mL	0.1590 mL	0.3180 mL	1.5902 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

4Oxoisotretinoin4 Oxoisotretinoin