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4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | TBD | 35 days | |
1 mg | TBD | 35 days | |
5 mg | TBD | 35 days | |
10 mg | TBD | 35 days |
Description | 4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid. |
Molecular Weight | 172.224 |
Formula | C9H16O3 |
Cas No. | 7439-43-2 |
Relative Density. | 0.999 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | Ethanol:PBS (pH 7.2)(1:6): 0.5 mg/mL (2.9 mM), Sonication is recommended. DMF: 30 mg/mL (174.19 mM), Sonication is recommended. Ethanol: 30 mg/mL (174.19 mM), Sonication is recommended. DMSO: 30 mg/mL (174.19 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMF/Ethanol/DMSO
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