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4-hydroperoxy 2-Nonenal

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Catalog No. T36001Cas No. 7439-43-2

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.

4-hydroperoxy 2-Nonenal

4-hydroperoxy 2-Nonenal

😃Good
Catalog No. T36001Cas No. 7439-43-2
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Pack SizePriceAvailabilityQuantity
500 μgTBD35 days
1 mgTBD35 days
5 mgTBD35 days
10 mgTBD35 days
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Product Introduction

Bioactivity
Description
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Chemical Properties
Molecular Weight172.224
FormulaC9H16O3
Cas No.7439-43-2
Relative Density.0.999 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol:PBS (pH 7.2)(1:6): 0.5 mg/mL (2.9 mM), Sonication is recommended.
DMF: 30 mg/mL (174.19 mM), Sonication is recommended.
Ethanol: 30 mg/mL (174.19 mM), Sonication is recommended.
DMSO: 30 mg/mL (174.19 mM), Sonication is recommended.
Solution Preparation Table
DMF/Ethanol/DMSO
1mg5mg10mg50mg
5 mM1.1613 mL5.8064 mL11.6128 mL58.0639 mL
10 mM0.5806 mL2.9032 mL5.8064 mL29.0320 mL
20 mM0.2903 mL1.4516 mL2.9032 mL14.5160 mL
50 mM0.1161 mL0.5806 mL1.1613 mL5.8064 mL
100 mM0.0581 mL0.2903 mL0.5806 mL2.9032 mL

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