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4-oxo-2-Nonenal

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Catalog No. T35646Cas No. 103560-62-9
Alias 4-oxo-2-Nonenal, 4-ONE

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. [1] [2] It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity and has been widely used as a marker of lipid peroxidation.[1][2][3] 4-oxo-2-Nonenal is a more recently identified product of lipid peroxidation.[4][5][6] It actively modifies histidine and lysine residues on proteins and causes protein cross-linking. [7][8] 4-oxo-2-Nonenal also modifies 2'-deoxyguanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis.[4]

4-oxo-2-Nonenal

4-oxo-2-Nonenal

😃Good
Catalog No. T35646Alias 4-oxo-2-Nonenal, 4-ONECas No. 103560-62-9
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. [1] [2] It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity and has been widely used as a marker of lipid peroxidation.[1][2][3] 4-oxo-2-Nonenal is a more recently identified product of lipid peroxidation.[4][5][6] It actively modifies histidine and lysine residues on proteins and causes protein cross-linking. [7][8] 4-oxo-2-Nonenal also modifies 2'-deoxyguanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis.[4]
Pack SizePriceAvailabilityQuantity
500 μgTBD35 days
1 mgTBD35 days
5 mgTBD35 days
10 mgTBD35 days
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Product Introduction

Bioactivity
Description
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. [1] [2] It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity and has been widely used as a marker of lipid peroxidation.[1][2][3] 4-oxo-2-Nonenal is a more recently identified product of lipid peroxidation.[4][5][6] It actively modifies histidine and lysine residues on proteins and causes protein cross-linking. [7][8] 4-oxo-2-Nonenal also modifies 2'-deoxyguanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis.[4]
Alias4-oxo-2-Nonenal, 4-ONE
Chemical Properties
Molecular Weight154.209
FormulaC9H14O2
Cas No.103560-62-9
Relative Density.0.933 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 50 mg/mL (324.24 mM), Sonication is recommended.
DMSO: 50 mg/mL (324.24 mM), Sonication is recommended.
Ethanol: 50 mg/mL (324.24 mM), Sonication is recommended.
PBS (pH 7.2): 0.5 mg/mL (3.24 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMF/DMSO/Ethanol
1mg5mg10mg50mg
1 mM6.4847 mL32.4235 mL64.8471 mL324.2353 mL
DMF/DMSO/Ethanol
1mg5mg10mg50mg
5 mM1.2969 mL6.4847 mL12.9694 mL64.8471 mL
10 mM0.6485 mL3.2424 mL6.4847 mL32.4235 mL
20 mM0.3242 mL1.6212 mL3.2424 mL16.2118 mL
50 mM0.1297 mL0.6485 mL1.2969 mL6.4847 mL
100 mM0.0648 mL0.3242 mL0.6485 mL3.2424 mL

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Keywords

4 oxo 2 Nonenal4oxo2Nonenal
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