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Amthamine 2HCl

Name: Amthamine 2HCl
Brand: TargetMol
SKU: T50112
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T50112Cas No. 136604-58-5

Alias 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine 2HCl

5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride is a potent and selective antagonist of metabotropic glutamate receptor 5 (mGluR5). It has been shown to be effective in several neurological disorders, including fragile X syndrome, autism spectrum disorders, and addiction.

Amthamine 2HCl

Purity: 95.00%

Catalog No. T50112Alias 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine 2HClCas No. 136604-58-5

Pack Size	Price	Availability
1 mg	$215	In Stock
2 mg	$323	In Stock
5 mg	$497	In Stock
10 mg	$723	In Stock
25 mg	$1,130	In Stock
50 mg	$1,520	In Stock
100 mg	$1,980	In Stock
500 mg	$3,970	In Stock

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Purity:95.00%

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COA HNMR LCMS

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Product Introduction

Bioactivity

Description	5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride is a potent and selective antagonist of metabotropic glutamate receptor 5 (mGluR5). It has been shown to be effective in several neurological disorders, including fragile X syndrome, autism spectrum disorders, and addiction.
Alias	5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine 2HCl

Chemical Properties

Molecular Weight	230.159
Formula	C₆H₁₃Cl₂N₃S
Cas No.	136604-58-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 14.67 mg/mL (63.73 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3448 mL	21.7241 mL	43.4482 mL	217.2411 mL
5 mM	0.8690 mL	4.3448 mL	8.6896 mL	43.4482 mL
10 mM	0.4345 mL	2.1724 mL	4.3448 mL	21.7241 mL
20 mM	0.2172 mL	1.0862 mL	2.1724 mL	10.8621 mL
50 mM	0.0869 mL	0.4345 mL	0.8690 mL	4.3448 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine5 (2 aminoethyl) 4 methyl 1,3 thiazol 2 amine dihydrochloride5(2aminoethyl)4methyl1,3thiazol2amine dihydrochloride