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6β-Naltrexol
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Catalog No. T85517Cas No. 49625-89-0
Alias 6β-Hydroxynaltrexone
6β-Naltrexol (6β-Hydroxynaltrexone), recognized as the primary metabolite of Naltrexone, functions as a peripherally selective opioid antagonist. It specifically targets and inhibits the opioid effects in the gastrointestinal tract of human subjects and also reduces morphine-induced slowing of gastrointestinal transit [1].
6β-Naltrexol
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Catalog No. T85517Alias 6β-HydroxynaltrexoneCas No. 49625-89-0
6β-Naltrexol (6β-Hydroxynaltrexone), recognized as the primary metabolite of Naltrexone, functions as a peripherally selective opioid antagonist. It specifically targets and inhibits the opioid effects in the gastrointestinal tract of human subjects and also reduces morphine-induced slowing of gastrointestinal transit [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 6β-Naltrexol (6β-Hydroxynaltrexone), recognized as the primary metabolite of Naltrexone, functions as a peripherally selective opioid antagonist. It specifically targets and inhibits the opioid effects in the gastrointestinal tract of human subjects and also reduces morphine-induced slowing of gastrointestinal transit [1]. |
| Alias | 6β-Hydroxynaltrexone |
| Molecular Weight | 343.42 |
| Formula | C20H25NO4 |
| Cas No. | 49625-89-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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