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9(R)-HODE is one of several monohydroxylated products of linoleic acid. All known mammalian lipoxygenases appear to catalyze the oxygenation of arachidonic and linoleic acid to give products having strictly the (S) configuration at the site of oxygen insertion. However, both human umbilical vein endothelial cells and bovine aorta endothelial cells have been shown to produce 9(R)-HODE when incubated with linoleic acid. The physiological function of 9(R)-HODE and the enzyme that catalyzes its formation have not been determined.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | 188 € | 35 days | |
50 μg | 361 € | 35 days | |
100 μg | 603 € | 35 days | |
250 μg | 1.406 € | 35 days |
Description | 9(R)-HODE is one of several monohydroxylated products of linoleic acid. All known mammalian lipoxygenases appear to catalyze the oxygenation of arachidonic and linoleic acid to give products having strictly the (S) configuration at the site of oxygen insertion. However, both human umbilical vein endothelial cells and bovine aorta endothelial cells have been shown to produce 9(R)-HODE when incubated with linoleic acid. The physiological function of 9(R)-HODE and the enzyme that catalyzes its formation have not been determined. |
Molecular Weight | 296.44 |
Formula | C18H32O3 |
Cas No. | 10075-11-3 |
Relative Density. | 0.970 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: >50 mg/mL (per Rao Maddipati) PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE) Ethanol: >50 mg/mL (per Rao Maddipati) DMF: >50 mg/mL (per Rao Maddipati) |
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