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AP1867-2-(carboxymethoxy)

AP1867-2-(carboxymethoxy)
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
Catalog No. T18611Cas No. 2230613-03-1
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AP1867-2-(carboxymethoxy)

Catalog No. T18611Alias PROTAC FKBP12-binding moiety 2Cas No. 2230613-03-1
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
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Product Introduction

Bioactivity
Description
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
In vitro
dTAG molecules engage FKBP12F36V and CRBN[1].
AliasPROTAC FKBP12-binding moiety 2
Chemical Properties
Molecular Weight693.78
FormulaC38H47NO11
Cas No.2230613-03-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

AP1867 2 (carboxymethoxy)AP-1867-2-(carboxymethoxy)AP18672(carboxymethoxy)AP1867-2-(carboxymethoxy)
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