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AR-13324 analog mesylate

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Catalog No. T10357

AR-13324 analog mesylate, an inhibitor of Rho-kinase and the norepinephrine transporter, reduces intraocular pressure in normotensive monkey eyes.

AR-13324 analog mesylate

AR-13324 analog mesylate

😃Good
Catalog No. T10357
AR-13324 analog mesylate, an inhibitor of Rho-kinase and the norepinephrine transporter, reduces intraocular pressure in normotensive monkey eyes.
Pack SizePriceAvailabilityQuantity
2 mg197 €Backorder
5 mg295 €Backorder
10 mg420 €Backorder
50 mg1.256 €Backorder
100 mgInquiryBackorder
200 mgInquiryBackorder
1 mL x 10 mM (in DMSO)409 €Backorder
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Product Introduction

Bioactivity
Description
AR-13324 analog mesylate, an inhibitor of Rho-kinase and the norepinephrine transporter, reduces intraocular pressure in normotensive monkey eyes.
Chemical Properties
Molecular Weight631.72
FormulaC29H33N3O9S2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 28 mg/mL (44.32 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5830 mL7.9149 mL15.8298 mL79.1490 mL
5 mM0.3166 mL1.5830 mL3.1660 mL15.8298 mL
10 mM0.1583 mL0.7915 mL1.5830 mL7.9149 mL
20 mM0.0791 mL0.3957 mL0.7915 mL3.9574 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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