Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aprocitentan D4 (ACT-132577 D4) is a deuterium-labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is a dual ETA/ETB antagonist (IC50s: 3.4 nM and 987 nM; pA2s: 6.7 and 5.5).
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Description | Aprocitentan D4 (ACT-132577 D4) is a deuterium-labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is a dual ETA/ETB antagonist (IC50s: 3.4 nM and 987 nM; pA2s: 6.7 and 5.5). |
Targets&IC50 | ETB:5.5, ETB:987 nM, ETA:3.4 nM, ETA:6.7(pA2) |
Synonyms | ACT-132577 D4 |
Molecular Weight | 550.22 |
Formula | C16H10D4Br2N6O4S |
CAS No. | T10351 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Aprocitentan D4 T10351 Others Aprocitentan D-4 ACT-132577 D4 inhibitor inhibit