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Fusarochromanone
🥰Excellent
Catalog No. T24075Cas No. 802915-53-3
Alias NSC-627608, NSC 627608, FC-101, FC101, FC 101
Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium marcescens with potent antiangiogenic, anticancer and antimalarial activities. Fusarochromanone induces cell death in COS7 and HEK293 cells through activation of the JNK pathway.
Fusarochromanone
🥰Excellent
Purity: 96.39%
Catalog No. T24075Alias NSC-627608, NSC 627608, FC-101, FC101, FC 101Cas No. 802915-53-3
Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium marcescens with potent antiangiogenic, anticancer and antimalarial activities. Fusarochromanone induces cell death in COS7 and HEK293 cells through activation of the JNK pathway.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $490 | In Stock | |
| 5 mg | $1,130 | In Stock | |
| 10 mg | $1,520 | In Stock | |
| 25 mg | $2,250 | In Stock | |
| 50 mg | $2,970 | In Stock |
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Purity:96.39%
ee:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium marcescens with potent antiangiogenic, anticancer and antimalarial activities. Fusarochromanone induces cell death in COS7 and HEK293 cells through activation of the JNK pathway. |
| In vitro | Fusarochromanone (10 μM; 24 hours) treatment of HaCaT and P9-WT cell lines resulted in cells being in the G2 and M phases of the cell cycle for both cell lines[1]. |
| In vivo | Fusarochromanone (8 mg/kg; administered intraperitoneally 5 days per week for 3.5 weeks) treatment of SCID Beige mice inoculated with SRB12-p9 cells resulted in a 30% reduction in tumor volume. |
| Alias | NSC-627608, NSC 627608, FC-101, FC101, FC 101 |
| Molecular Weight | 292.33 |
| Formula | C15H20N2O4 |
| Cas No. | 802915-53-3 |
| Smiles | NC1=C2C(=CC=C1C(C[C@H](CO)N)=O)OC(C)(C)CC2=O |
| Relative Density. | 1.267 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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