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Azide-PEG6-Tos is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | 7-10 days | |
5 mg | $59 | 7-10 days | |
10 mg | $84 | 7-10 days | |
25 mg | $136 | 7-10 days | |
50 mg | $196 | 7-10 days | |
100 mg | $295 | 7-10 days | |
500 mg | $837 | 7-10 days |
Description | Azide-PEG6-Tos is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase and the other targets the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 461.53 |
Formula | C19H31N3O8S |
Cas No. | 906007-10-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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