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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bromo-PEG5-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker utilized in the construction of PROteolysis TArgeting Chimeras (PROTACs), which are heterobifunctional molecules designed to induce protein degradation[1]. |
In vitro | PROTACs are composed of two ligands linked together: one targets an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade specific proteins [1]. |
Molecular Weight | 465.31 |
Formula | C16H34BrO8P |
Cas No. | 1446282-41-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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