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Bromo-PEG6-alcohol is a PEG-based linker for PROTACs (Proteolysis Targeting Chimeras) that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Bromo-PEG6-alcohol is a PEG-based linker for PROTACs (Proteolysis Targeting Chimeras) that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade these target proteins [1]. |
Molecular Weight | 345.23 |
Formula | C12H25BrO6 |
Cas No. | 136399-05-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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