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Freselestat

Catalog No. T31877Cas No. 208848-19-5
Alias ONO-PO 736, ONO-6818, ONO6818, ONO 6818

Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9, thereby decreasing inflammatory mediators during simulated cardiopulmonary bypass.

Freselestat
Other Forms of Freselestat:
Freselestat quarterhydrateT62846
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Freselestat

Catalog No. T31877Alias ONO-PO 736, ONO-6818, ONO6818, ONO 6818Cas No. 208848-19-5
Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9, thereby decreasing inflammatory mediators during simulated cardiopulmonary bypass.
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10 mg$78335 days
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Product Introduction

Bioactivity
Description
Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9, thereby decreasing inflammatory mediators during simulated cardiopulmonary bypass.
Targets&IC50
Neutrophil elastase:12.2 nM (Ki)
AliasONO-PO 736, ONO-6818, ONO6818, ONO 6818
Chemical Properties
Molecular Weight452.51
FormulaC23H28N6O4
Cas No.208848-19-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

FreselestatONO-PO736ONO-PO-736
Related Tags: buy Freselestat | purchase Freselestat | Freselestat cost | order Freselestat | Freselestat chemical structure | Freselestat formula | Freselestat molecular weight
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