H100

H100 is a Cl- transport inhibitor, no effect against KCl cotransporter. It has partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger.

Catalog No. T11528Cas No. 643727-55-3

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H100

Catalog No. T11528Cas No. 643727-55-3

H100 is a Cl- transport inhibitor, no effect against KCl cotransporter. It has partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger.

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Pack Size	Price	Availability
25 mg	$1,520	6-8 weeks
50 mg	$1,980	6-8 weeks
100 mg	$2,500	6-8 weeks

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Product Introduction

Bioactivity

Description	H100 is a Cl- transport inhibitor, no effect against KCl cotransporter. It has partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger.
In vitro	H100 (0.1 mM) demonstrates significant inhibitory activity on chloride transport in human erythrocytes, with 63% and 74% inhibition of the NaK2Cl cotransporter (NKCC) and the Band 3 anion exchanger (AE), respectively. It acts as a Cl- transport inhibitor, selectively targeting NKCC and AE without affecting the KCl cotransporter (KCC).

Chemical Properties

Molecular Weight	388.4
Formula	C₁₈H₁₆N₂O₆S
Cas No.	643727-55-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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Keywords

H 100H100H-100