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HG6-64-1

Name: HG6-64-1
Brand: TargetMol
SKU: T15480
Price: 196 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T15480Cas No. 1315329-43-1

Alias HMSL 10017-101-1

HG6-64-1 is a potent and selective inhibitor of B-Raf, with an IC50 of 0.09 μM on B-raf V600E-transformed Ba/F3 cells.

HG6-64-1

😃Good

Catalog No. T15480Alias HMSL 10017-101-1Cas No. 1315329-43-1

HG6-64-1 is a potent and selective inhibitor of B-Raf, with an IC50 of 0.09 μM on B-raf V600E-transformed Ba/F3 cells.

Pack Size	Price	Availability
2 mg	$198	8-10 weeks
5 mg	$347	8-10 weeks
25 mg	$1,140	8-10 weeks
50 mg	$1,490	8-10 weeks
100 mg	$1,990	8-10 weeks
1 mL x 10 mM (in DMSO)	$442	8-10 weeks

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Product Introduction

Bioactivity

Description	HG6-64-1 is a potent and selective inhibitor of B-Raf, with an IC50 of 0.09 μM on B-raf V600E-transformed Ba/F3 cells.
Targets&IC50	B-Raf (V600E):0.09 μM (in Ba/F3 cells)
Alias	HMSL 10017-101-1

Chemical Properties

Molecular Weight	577.64
Formula	C₃₂H₃₄F₃N₅O₂
Cas No.	1315329-43-1
Relative Density.	1.295 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (173.12 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7312 mL	8.6559 mL	17.3118 mL	86.5591 mL
5 mM	0.3462 mL	1.7312 mL	3.4624 mL	17.3118 mL
10 mM	0.1731 mL	0.8656 mL	1.7312 mL	8.6559 mL
20 mM	0.0866 mL	0.4328 mL	0.8656 mL	4.3280 mL
50 mM	0.0346 mL	0.1731 mL	0.3462 mL	1.7312 mL
100 mM	0.0173 mL	0.0866 mL	0.1731 mL	0.8656 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

HG-6-64-1HG6 64 1HG6-64-1HG6641