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HS-PEG3-CH2CH2N3

Catalog No. T18023Cas No. 1347750-79-1
Alias Thiol-PEG3-C2-azide

HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

HS-PEG3-CH2CH2N3

HS-PEG3-CH2CH2N3

Catalog No. T18023Alias Thiol-PEG3-C2-azideCas No. 1347750-79-1
HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
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Product Introduction

Bioactivity
Description
HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
In vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
AliasThiol-PEG3-C2-azide
Chemical Properties
Molecular Weight235.3
FormulaC8H17N3O3S
Cas No.1347750-79-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

HS-PEG3-CH2CH2N3HS-PEG-3-CH2CH2N3HS PEG3 CH2CH2N3HSPEG3CH2CH2N3
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