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K114

Name: K114
Brand: TargetMol
SKU: T19018
Price: 50 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T19018Cas No. 872201-12-2

K114 binds tightly to amyloid fibrils (EC50: 20-30 nM). K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).

K114

Catalog No. T19018Cas No. 872201-12-2

K114 binds tightly to amyloid fibrils (EC50: 20-30 nM). K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).

Pack Size	Price	Availability	Quantity
10 mg	$385	35 days

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Product Introduction

Bioactivity

Description	K114 binds tightly to amyloid fibrils (EC50: 20-30 nM). K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).
In vitro	The unusually low buffer fluorescence of K114 is due to self-quenching in sedimentable aggregates or micelles which upon interacting with amyloid fibrils undergo an enhancement in fluorescence intensity and shifts in the excitation and emission spectra [1].

Chemical Properties

Molecular Weight	393.27
Formula	C₂₂H₁₇BrO₂
Cas No.	872201-12-2

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (254.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5428 mL	12.7139 mL	25.4278 mL	127.1391 mL
5 mM	0.5086 mL	2.5428 mL	5.0856 mL	25.4278 mL
10 mM	0.2543 mL	1.2714 mL	2.5428 mL	12.7139 mL
20 mM	0.1271 mL	0.6357 mL	1.2714 mL	6.3570 mL
50 mM	0.0509 mL	0.2543 mL	0.5086 mL	2.5428 mL
100 mM	0.0254 mL	0.1271 mL	0.2543 mL	1.2714 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

K-114K 114K114