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L-NIL dihydrochloride

Catalog No. T25749Cas No. 159190-45-1
Alias N-Iminoethyl-L-lysine dihydrochloride, L-NIL HCl

L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major.

L-NIL dihydrochloride
Other Forms of L-NIL dihydrochloride:
L-NIL hydrochlorideT22914150403-89-7
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L-NILT1180553774-63-3
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L-NIL dihydrochloride

Catalog No. T25749Alias N-Iminoethyl-L-lysine dihydrochloride, L-NIL HClCas No. 159190-45-1
L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major.
Pack SizePriceAvailabilityQuantity
10 mg$9835 days
50 mg$37035 days
100 mg$69035 days
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Product Introduction

Bioactivity
Description
L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response
Targets&IC50
iNOS (mouse):3.3 μM (IC50), cNOS (rat brain):92 μM (IC50)
AliasN-Iminoethyl-L-lysine dihydrochloride, L-NIL HCl
Chemical Properties
Molecular Weight260.16
FormulaC8H19Cl2N3O2
Cas No.159190-45-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

LNIL dihydrochlorideL-NILN-Iminoethyl-L-lysineN-Iminoethyl-L-lysine DihydrochlorideL NIL dihydrochlorideL-NIL Dihydrochloride
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